Save
A save is a term derived from "saving throw", a term originating from tabletop role playing games as a defensive check to see if a player will take or avoid a harmful effect. Saves are usually referred to in the context "a (attribute) save of difficulty (number)".
By default, this is a 1d201-20 (Avg: 10.5) dice roll that has the attribute's modifier added to the result. If this is greater than the difficulty specified, the "save" is successful and the attempted effect to apply will be ignored.
If a save is against multiple attributes, the best modifier is used.
Some saves are also modified by an attacker's attribute, which adds to the save difficulty.
Most saves fail when the game rolls a natural 1 (i.e. "critical failure") and succeed on a natural 20 regardless of difficulty and bonuses, meaning you always have at least a 5% chance of success and at least a 5% chance of failure.
Saves include "Vs." tagging to designate what kind of effect they are, so save modifiers can be provided for particular scopes. If any part of a save modifier's scope matches to a part of the save's Vs., the save modifier applies.
You can see the details of all saving throws performed in the game with the debug option "Show saving throw debug text".
Movement-Related Saves
Certain items grant a bonus or penalty to movement-related saves, including 
magnetized boots (+4), 
rocket skates (-4), 
motorized treads (+4), cleated footwear (+2-4), and stability-based cooking effects (+6).
| Source | Attribute | Vs | Difficulty | Attacker Attribute |
|---|---|---|---|---|
 asphalt (walking on)
|
Strength, Agility | Tar Stuck Restraint | 4 to 24 | |
 crypt ferret bite (initial)
|
Agility | LatchOn Move Drag Restraint | 25 | Agility |
| crypt ferret bite (move)
|
Strength | LatchOn Move Drag Restraint | 25 | Strength |
| crypt ferret bite (ongoing)
|
Strength | LatchOn Continue Grab Restraint Escape | 25 | Strength |
 gel (walking on)
|
Agility | Gel Slip Move | 5 to 24 | |
 honey (walking on)
|
Strength, Agility | Honey Stuck Restraint | 1 to 24 | |
| Hook and Drag (initial) | Strength | HookAndDrag Move Grab Restraint | 20 | Strength |
| Hook and Drag (ongoing) | Strength | HookAndDrag Continue Grab Restraint Escape | 20 | Strength |
 ink (walking on)
|
Agility | Ink Slip Move | 5 to 24 | |
| Kickback | Strength | Rifle Kickback Knockback | 15 | Strength |
 leather whip (initial)
|
Agility | LatchOn Move Drag Restraint | 14 | Agility |
| leather whip (move)
|
Strength | LatchOn Move Drag Restraint | 14 | Strength |
| leather whip (ongoing)
|
Strength | LatchOn Continue Grab Restraint Escape | 14 | Strength |
 madpole jaws (initial)
|
Agility | LatchOn Move Drag Restraint | 15 | Agility |
| madpole jaws (move)
|
Strength | LatchOn Move Drag Restraint | 15 | Strength |
| madpole jaws (ongoing)
|
Strength | LatchOn Continue Grab Restraint Escape | 15 | Strength |
 maghammer (initial, move)
|
Strength | LatchOn Move Drag Restraint | 20 | Strength |
| maghammer (ongoing)
|
Strength | LatchOn Continue Grab Restraint Escape | 20 | Strength |
 molten wax (walking on)
|
Strength, Agility | Wax Stuck Restraint | 1 to 24 | |
 oil (walking on)
|
Agility | Oil Slip Move | 5 to 24 | |
 sap (walking on)
|
Strength, Agility | Sap Stuck Restraint | 1 to 24 | |
 sewage eel
|
Agility | Eel Spawn Knockdown | 16 | |
 slime (walking on)
|
Agility | Slime Slip Move | 5 to 24 | |
 Slog of the Cloaca (ranged) / Bilge Sphincter
|
Strength, Agility | Slog Glands Knockdown | 17 | |
 Stopsvalinn
|
Willpower | Robot Stop Restraint | 18 | |
Stuck (grabbed by  jilted lover)
|
Strength | Grab Stuck Restraint | 20 | |
Stuck (grabbed by  locking machine arm)
|
Strength | Grab Stuck Restraint | 25 | |
Stuck (grabbed by  mimic)
|
Strength | Grab Stuck Restraint | 20 | |
Stuck (stuck in  web or  phase web created by zone generation)
|
Strength | Web Stuck Restraint | 15 | |
| Stuck (stuck in web or phase web created by Spider Webs)
|
Strength | Web Stuck Restraint | 15 + mutation level | |
Stuck (stuck in web created by  Spinnerets)
|
Strength | Web Stuck Restraint | 14 + (2 * mutation level) | |
| Stuck (stuck in phase web created by Spinnerets)
|
Strength | Web Stuck Restraint | 18 + (2 * mutation level) | |
Stuck (hit by  cast net)
|
Strength | Entangle Stuck Restraint | 25 | |
| Stuck (hit by honeyed, waxen, sugary, or tarry pseudopod)
|
Strength | Stuck Restraint | 15 | |
| Stuck (in large pool of liquid as it freezes) | Strength | Frozen Stuck Restraint | 15 | |
 water (walking on frozen)
|
Agility | Ice Slip Move | 10 |
Other Saves
| Source | Attribute | Vs | Difficulty | Attacker Attribute |
|---|---|---|---|---|
 black ooze (going prone in)
|
Toughness | Ooze Disease | 13 | |
 blast cannon
|
Toughness | Stunning Force Stun | 18 | |
| Bleeding | Toughness | Bleeding | 20 - 1 per save failed (refer to bleeding page for more detail) | |
| Bombs (disarming) | Intelligence | Tinkering Bomb Disarm | 9 + (mark of explosive * 3) - 4 for Gadget Inspector - 4 for Lay Mine / Set Bomb | |
 confusion gas
|
Toughness | Confusion Inhaled Gas | 5 + gas level + gas density / 10 | |
 decarbonizer
|
Agility | Decarbonizer Beam | 20 | Agility |
 Frondzie
|
Willpower | Verbal Taunt | 12 | Ego |
| fungal spores | Toughness | Fungal Disease Contact Gas | 10 + 8 if from Klanq infection | |
 green goo (going prone in)
|
Toughness | Goo Poison | 30 | |
| Glotrot | Toughness | Glotrot Disease Onset | 13 | |
 galgal's  naser cannon grounding effect
|
Agility | Normality Naser Grounding | 40 - target's flight level | |
 gamma moth
|
Toughness | Mutation | 20 | |
 green jell
|
Toughness | Melee Injected Damaging Poison | 20 | |
| Holographic bleeding | Intelligence | Hologram Illusion | 20 - 1 per save failed | |
 hologram bracelet
|
Intelligence | Hologram Illusion Distraction | 15 | |
 ickslug
|
Toughness | Melee Injected Damaging Poison | 20 | |
| Immobilized | Agility | Immobilization | 20 - 1 per 5 turns | |
| Ironshank | Toughness | Ironshank Disease Onset | 13 | |
 lithofex
|
Toughness | Lithofex Stoning Gaze Beam | 20 | Ego |
| Mines (disarming) | Intelligence | Tinkering Mine Disarm | 9 + (mark of explosive * 3) - 4 for Gadget Inspector - 4 for Lay Mine / Set Bomb | |
| Monochrome | Toughness | Monochrome Disease Onset | 13 | |
| Morphogenetic | Willpower | MorphicShock Daze | 10 + 1 per 5 points of damage done + (available compute power / 3) - 5 for analgesia | |
| Normality (failing an attempt to overcome it with a mutation) | Willpower | RealityStabilization Daze | 20 | |
 phase spider
|
Toughness | Melee Injected Phase Damaging Poison | 20 | |
 poison-tipped spear
|
Toughness | Injected Damaging Poison | 15 | |
| Shield Slam | Strength | Shield Slam | 20 | Strength |
 sleep gas
|
Toughness | Sleep Inhaled Gas | 5 + gas level + gas density / 10 | |
| Slog of the Cloaca (melee)
|
Toughness | Melee Injected Damaging Poison | 20 | |
 strip fly
|
Agility | Disarm | 10 | Agility |
| Stinger (Confusing Venom) | Toughness | Stinger Injected Confusion Poison | 14 + mutation level | |
| Stinger (Paralyzing Venom) | Toughness | Stinger Injected Paralysis Poison | 14 + mutation level | |
| Stinger (Poisoning Venom) | Toughness | Stinger Injected Damaging Poison | 14 + mutation level | |
| Stunning Force | Toughness | Stunning Force Stun | 15 + mutation level | |
| Stunned | Toughness | Stun | 15 | |
| Swipe (defensive stance) | Strength | Disarm | 25 | Agility |
| Tonic overdose | Toughness | Overdose | 16 + 3 per tonic over limit |